Summary: Epigenetic Changes and beLIVELY Vita
- Epigenetic changes : adaptations in gene expression that are influenced by environmental factors and aging processes.
- Aging process due to epigenetic changes : accumulation of modifications leads to gene regulation errors, impairment of important cellular functions and promotion of age-related diseases.
Combating with beLIVELY Vita :
- Glycine : Supports the mitochondrial epigenome and improves cellular health.
- Turmeric : Turmeric helps fight epigenetic changes by inhibiting DNA methyltransferases (DNMTs) and histone deacetylases (HDACs), which increases gene expression and protects DNA integrity through antioxidant properties.
- Alpha-ketoglutarate : Supports TET enzymes in DNA demethylation and stabilizes the epigenome.
- Polyphenols : Polyphenols such as resveratrol and EGCG (from green tea) have antioxidant and anti-inflammatory properties and can inhibit epigenetic enzymes such as histone deacetylases (HDACs), which positively affects gene expression.
- Vitamin C : Vitamin C is a cofactor for TET enzymes, which play a crucial role in DNA demethylation, and increases the activity of these enzymes, supporting epigenetic regulation.
These components in beLIVELY Vita can work synergistically to minimize the negative effects of epigenetic aging processes and thus promote health and longevity.
Epigenetic Changes and Their Relationship to Aging
Epigenetic changes include adjustments in gene expression that are not caused by changes in DNA sequence, but by mechanisms such as DNA methylation, histone modifications, and non-coding RNA activities. These changes can be influenced by environmental factors, lifestyle, and over time by aging processes. They play a central role in the development and progression of numerous age-related diseases, as well as in general aging dynamics.
Epigenetic modifications can accumulate over the course of life and often lead to decreasing precision in gene regulation. This impairs critical cellular processes such as DNA repair, cell division and cell death. Dysregulation of these processes by epigenetic changes can contribute to the development of age-related pathologies such as cancer, cardiovascular disease and neurodegenerative disorders.
Combating epigenetic changes through beLIVELY Vita
Some natural substances contained in beLIVELY Vita have been shown to be beneficial in influencing the aging epigenome:
Glycine
Glycine has been shown to benefit the aging epigenome, particularly in mitochondria, which have their own DNA that can be methylated. This amino acid may help support mitochondrial functions and improve overall cellular health ( R ).
Alpha-ketoglutarate
This ingredient helps the epigenetic TET enzymes perform their functions, which is essential for maintaining DNA demethylation and thus for proper gene expression. Alpha-ketoglutarate may thus contribute to the stabilization of the epigenome and mitigate age-related epigenetic changes ( R , R , R ).
turmeric
Curcumin, the active ingredient in turmeric, plays a significant role in combating epigenetic alterations. Curcumin can inhibit the activity of DNA methyltransferases (DNMTs), preventing the epigenetic silencing of tumor suppressor genes and promoting their expression. Furthermore, curcumin also inhibits histone deacetylases (HDACs), leading to looser chromatin structure and increased gene expression ( R ).
These ingredients in beLIVELY Vita offer a comprehensive approach to supporting macroautophagy and can help minimize the negative effects of impaired cellular self-cleaning.
What is beLIVELY Vita?
What is beLIVELY Vita?
beLIVELY Vita is an all-in-one dietary supplement and the most researched and scientifically validated solution that addresses the 12 causes of aging .
Our formulation was developed based on over 400 studies to slow the rate of aging.
What does beLIVELY Vita do?
What does beLIVELY Vita do?
beLIVELY Vita targets 12 scientific causes of aging to slow the pace of aging.
It improves energy levels, skin health, mood, and cognitive function over time.
Who is it suitable for?
Who is it suitable for?
beLIVELY Vita is ideal for anyone who wants to take their longevity, energy, and health to the next level. It was specifically developed to combat the 12 main causes of aging and supports you in feeling younger, more vital, and more productive – whether you want to take preventative measures or compensate for existing deficiencies.
The 12 Main Causes of Aging
Learn more about the scientific causes that make our bodies age.