Summary: Loss of proteostasis and beLIVELY Vita
- Loss of proteostasis : Impairment of the cellular ability to correctly fold and degrade proteins leads to the accumulation of toxic protein aggregates.
- Aging process due to loss of proteostasis : Decrease in the efficiency of proteasomes and autophagic processes with age. Accumulation of misfolded proteins accelerates cellular dysfunction and aging.
Combating with beLIVELY Vita
- Vitamin C : Reduces oxidative stress and supports correct protein folding.
- Rhodiola Rosea : Strengthens cellular stress resistance and promotes proteostasis.
- Green Tea Extract (EGCG) : Helps prevent protein aggregation, supports protein folding.
This combination of ingredients in beLIVELY Vita could help minimize the loss of proteostasis and thus promote overall cellular health and longevity.
The loss of proteostasis and the relationship with aging
Proteostasis refers to the maintenance of a balance in the production, folding, transport and degradation of proteins within a cell. This balance is crucial for the proper functioning of cells and tissues. With age or due to stressors such as heat, toxins or pathogens, this balance can be disrupted, leading to a phenomenon known as loss of proteostasis. This results in the accumulation of misfolded or aggregated proteins that can be toxic to cells and contribute to various diseases such as Alzheimer's, Parkinson's and Huntington's.
The aging process due to the loss of proteostasis
The ability of cells to effectively fold and degrade proteins declines with age. Proteasomal degradation and autophagic activity, both of which help maintain proteostasis, become less efficient over time. This leads to the accumulation of damaged proteins and protein complexes that can disrupt cellular functions and accelerate the aging process. The accumulation of these protein aggregates can also trigger or exacerbate neurodegenerative diseases and is associated with reduced cell viability and function.
Combating the loss of proteostasis with beLIVELY Vita
Some ingredients in beLIVELY Vita may help combat the loss of proteostasis:
Vitamin C
As an antioxidant, vitamin C can help stabilize the cellular environment and reduce oxidative stress, which can contribute to protein misfolding. This supports the cellular ability to properly fold and process proteins.
Rhodiola Rosea Root Extract
Rhodiola promotes cellular stress resistance and may help strengthen cellular defense mechanisms against the stress that leads to the loss of proteostasis. Its adaptogenic properties may improve overall cellular health and function, which in turn supports proteostasis.
Green tea extract (standardized to 50% EGCG)
Epigallocatechin gallate (EGCG), a major component of green tea, has been shown to support protein folding and prevent the formation of protein aggregates. This could be particularly useful in the prevention of diseases such as Alzheimer's disease, where protein aggregation plays a role.
These ingredients in beLIVELY Vita offer a comprehensive approach to supporting macroautophagy and can help minimize the negative effects of impaired cellular self-cleaning.
What is beLIVELY Vita?
What is beLIVELY Vita?
beLIVELY Vita is an all-in-one dietary supplement and the most researched and scientifically validated solution that addresses the 12 causes of aging .
Our formulation was developed based on over 400 studies to slow the rate of aging.
What does beLIVELY Vita do?
What does beLIVELY Vita do?
beLIVELY Vita targets 12 scientific causes of aging to slow the pace of aging.
It improves energy levels, skin health, mood, and cognitive function over time.
Who is it suitable for?
Who is it suitable for?
beLIVELY Vita is ideal for anyone who wants to take their longevity, energy, and health to the next level. It was specifically developed to combat the 12 main causes of aging and supports you in feeling younger, more vital, and more productive – whether you want to take preventative measures or compensate for existing deficiencies.
The 12 Main Causes of Aging
Learn more about the scientific causes that make our bodies age.