Summary: Cellular Senescence and beLIVELY Vita
- Cellular senescence : Condition in which cells stop dividing but remain active and secrete various molecules, known as senescent cells.
- Aging process through cellular senescence : Senescent cells accumulate with age and produce the senescence-associated secretory phenotype (SASP). SASP leads to tissue damage, promotes inflammation and contributes to the development of age-related diseases. Impairs tissue regeneration and repair, which accelerates the aging process.
Combating cellular senescence with beLIVELY Vita :
- Fisetin : Has senolytic properties that specifically remove senescent cells and reduce the negative effects of SASP.
- Rhodiola Rosea Root Extract : Adaptogen that may slow stress-induced cellular senescence by improving cellular resistance to oxidative and stress-induced damage.
- Polyphenol : The green tea extract contained in beLIVELY Vita, particularly epigallocatechin gallate (EGCG), has antioxidant and anti-inflammatory properties and exhibits senolytic activity by specifically removing senescent cells. EGCG reduces senescence markers and pro-inflammatory factors, thereby improving tissue health and maintaining cell function, which may help extend lifespan.
This combination of ingredients in beLIVELY Vita helps reduce the effects of cellular senescence, thereby promoting overall cellular health and longevity.
Cellular Senescence and its Relationship to Aging
The aging process through cellular senescence
Cellular senescence refers to a condition in which cells lose the ability to divide but continue to actively metabolize and secrete various molecules. These cells, often referred to as "senescent cells," occur as a natural response to aging processes or in response to cellular stress and damage. Cellular senescence serves as a protective measure against the uncontrolled cell division that could lead to cancer by stopping the growth of potentially malignant cells.
As we age, senescent cells accumulate in the body, which has several negative effects. These cells secrete pro-inflammatory factors, growth factors, and proteolytic enzymes, a phenomenon known as the "senescence-associated secretory phenotype" (SASP). SASP can damage surrounding tissue, promote inflammatory processes, and contribute to the development of age-related diseases such as arthritis, Alzheimer's disease, and atherosclerosis. The presence of these cells and the factors they secrete can also hinder tissue regeneration and repair, further accelerating the aging process.
Combating cellular senescence with beLIVELY Vita
beLIVELY Vita contains several ingredients that can potentially counteract mechanisms of cellular senescence:
Fisetin
This flavonoid has been shown to possess potent senolytic activity, meaning it can specifically remove senescent cells. Fisetin reduces senescence markers and the secretion of pro-inflammatory factors, helping to mitigate the effects of SASP and improve overall tissue health ( R ).
Rhodiola Rosea Root Extract
Rhodiola is known for its adaptogenic and anti-stress properties. It may help modulate the cellular response to stress and thus slow the induction of senescence. Active components such as rosavins and salidrosides may increase cellular resistance to oxidative and stress-induced damage ( R ).
Polyphenol
The green tea extract in our beLIVELY Vita contains polyphenols, particularly epigallocatechin gallate (EGCG), which possesses antioxidant and anti-inflammatory properties. EGCG exhibits potent senolytic activity by specifically removing senescent cells. It reduces senescence markers and the secretion of pro-inflammatory factors, helping to mitigate the effects of the senescent secretory phenotype (SASP) and improve overall tissue health. Through these mechanisms, green tea extract may contribute to maintaining healthy cell function and extending lifespan ( R ).
These ingredients in beLIVELY Vita offer a comprehensive approach to supporting macroautophagy and can help minimize the negative effects of impaired cellular self-cleaning.
What is beLIVELY Vita?
What is beLIVELY Vita?
beLIVELY Vita is an all-in-one dietary supplement and the most researched and scientifically validated solution that addresses the 12 causes of aging .
Our formulation was developed based on over 400 studies to slow the rate of aging.
What does beLIVELY Vita do?
What does beLIVELY Vita do?
beLIVELY Vita targets 12 scientific causes of aging to slow the pace of aging.
It improves energy levels, skin health, mood, and cognitive function over time.
Who is it suitable for?
Who is it suitable for?
beLIVELY Vita is ideal for anyone who wants to take their longevity, energy, and health to the next level. It was specifically developed to combat the 12 main causes of aging and supports you in feeling younger, more vital, and more productive – whether you want to take preventative measures or compensate for existing deficiencies.
The 12 Main Causes of Aging
Learn more about the scientific causes that make our bodies age.