This is what happens when you take NMN!
hour 1
NMN penetrates the cells
According to research, NMN works fast . Preclinical studies on the pharmacokinetics of NMN suggest that it is absorbed from the intestine into the bloodstream within minutes and transported to the tissues within 10 to 30 minutes [1, 2]. That's when the magic (or biochemistry) begins!
The NMN is immediately used for NAD+ biosynthesis .
Research suggests that rapid uptake is enabled by an NMN-specific transporter called “Sic12a8.”
hour 5
More activity in the cells
Same day, more activity in cells . Human studies show that NAD+ metabolites in blood plasma increase continuously within the first few hours after NMN ingestion , indicating increased NAD+ utilization in cells and tissues [4].
Cells already use increased NAD+ levels to support hundreds of important cellular processes .
If you could communicate with your cells, they would definitely thank you! :)
Day 3
Happy mitochondria
NAD+ levels continue to rise and now benefit the power plants of your cells and the place where cellular energy is generated: the mitochondria.
A preclinical study has shown that three days of treatment of human kidney cells with NMN leads to increased mitochondrial replication [5]. An increased number of mitochondria enables more efficient energy production and metabolic regulation in the cell .
day 30
Up to 40% increase in NAD+
The fact is: After one month, the NAD+ level in the blood is up to 40% higher than when taking the first capsules.
They will remain at this level if you continue supplementing. This is according to a human clinical study that investigated NMN supplementation with a dose of 250 mg NMN per day in healthy adults [7].
Do you already feel the increased fitness?
week 6
Benefits for the muscles
We'll move from cells to systems, as aspects of your fitness can improve. A human clinical study showed that NAD+ is one of the most depleted metabolites in aging muscle, and that high NAD+ was associated with healthy muscle function [8].
Another clinical study found that oral administration of NMN at a dose of 250 mg per day for 6 weeks improved muscle strength and performance in healthy elderly men [19].
week 8
Improved skin
How does your skin look? Advanced glycation end products (AGEs) are markers of skin aging. A clinical study in healthy postmenopausal women found that eight weeks of NMN supplementation with 300 mg NMN per day led to a reduction in AGEs in the skin , which is considered a positive effect for skin aging [10].
week 10
Healthy insulin sensitivity
There's still more to do in your muscles after 10 weeks.
In a clinical study of prediabetic women, two important discoveries were made. The first was an increase in NMN metabolites in skeletal muscle tissue , suggesting that the muscles had more NAD+ available.
The second finding suggests that NMN can support healthy insulin sensitivity in skeletal muscle and regulate the expression of genes related to muscle remodeling—the turnover of muscle proteins, organelles, and cell populations. Study participants consumed 250 mg of NMN daily [11].
month 3
Faster walking and longer telomeres
Three months have passed, and you've measured 40% more NAD+ in your cells and tissues for 60 days. But what has changed physically in you? A lot, as clinical studies show!
One study found an improvement in gait speed (walking speed) in healthy elderly men taking 250 mg of NMN per day [9]. Another study found that telomere length in peripheral blood mononuclear cells doubled at a dose of 300 mg of NMN per day, indicating a younger biological age! [12].
month 6
It all starts to add up
A lot happens in six months - what has changed in your life?
With beLIVELY NMN, everything starts to add up to systemic health benefits . It sustainably supports multiple tissues and systems by attacking metabolic aging where it matters—in your cells.
Have you ever considered having your biological age determined? After 6 months of taking NMN, it may be significantly lower than before, because your cells have finally found the energy boost they needed – NMN !
1 year
Healthy aging and NAD+ go hand in hand
Congratulations on your first year of replenishing the NAD+ lost through aging. Research shows that NAD+ declines by up to 50% every 20 years .
It's important to maintain your NMN routine: Studies have shown that four weeks after discontinuing NMN, NAD+ levels returned to pre-supplementation levels [7]. Just like with exercise, sleep, and diet, consistency is key to long-term results.
Human studies are beginning to show that healthy aging and high NAD+ levels go hand in hand [8].
beLIVELY NMN helps you feel good as you age!
Because aging can be prevented...
Sources and studies
Sources and studies
[1] Yoshino, J., et al., Cell Metab. 14: 528–536 (2011).
[2] Mills, KF et al. Cell Metab. 24: 795–806 (2016).
[3] Grozio, A., et al., Nature Metabolism 1: 47-57 (2019).
[4] Irie, J., et al., Endocrine Journal 67 (2): 153-160 (2020).
[5] Nomiyama, T., et al., The Journal of Biochemistry 171 (3): 325-338 (2021).
[6] Fu, J., et al., J Biol Chem. 287 (29): 24460–24472 (2012).
[7] Okabe, K., et al., Frontiers in Nutrition 9: 868640 (2022).
[8] Igarashi, M. et al., NPG Aging 8: 5 (2022).
[9] Janssens, GE et al., Nat Aging 2: 254–263 (2022).
[10] Morita, Y. et al., Glycative Stress Research 9 (2): 33-41 (2022).
[11] Yoshino, M. et al., Science 372 (6547): 1224-1229 (2021).