What is NAD+?
NAD+ ( nicotinamide adenine dinucleotide ) is an essential coenzyme in every cell that plays a central role in energy metabolism and DNA repair and declines with age .
NAD+ as the key to vitality
Just as climbing to the highest point requires perseverance and determination, increasing NAD+ levels is crucial to reaching the peak of our vitality and health. With the right supports, like NMN, we can reach that peak and enjoy a long, healthy life.
NAD+ levels decrease with age
NAD+ is an essential coenzyme found in all cells and is crucial for energy production, DNA repair, and gene regulation. Elevated NAD+ levels are associated with longevity, while the natural decline with age can impair vital cellular functions.
Effects of low NAD+ levels
Reduced mitochondrial function
Reduced mitochondrial function
Mitochondria are the power plants of our cells that are responsible for energy production.
NAD+ is an important cofactor in cellular respiration, a process by which mitochondria extract energy from nutrients. When NAD+ levels drop, energy production in the mitochondria becomes less efficient, leading to an overall energy deficit in the body. This can manifest as fatigue, reduced physical performance, and general malaise.
reduction of sirtuin activity
reduction of sirtuin activity
Sirtuins are enzymes that play a key role in regulating cellular metabolism, inflammatory responses, and DNA repair. They are often referred to as "longevity proteins" because they help maintain cellular health and slow down the aging process.
However, the activity of sirtuins is directly dependent on NAD+. Low NAD+ levels therefore lead to reduced sirtuin activity, which can accelerate the aging process and increase the risk of age-related diseases.
impairment of DNA repair
impairment of DNA repair
Our DNA is constantly exposed to various stress factors that can cause damage. The body has repair mechanisms to repair this damage and preserve the integrity of the DNA.
NAD+ plays a crucial role in the activation of DNA repair enzymes. If NAD+ is deficient, the body's ability to repair DNA damage is limited.
This can lead to the accumulation of genetic damage that increases the risk of cancer and other degenerative diseases.
Benefits of increased NAD+ levels
Improved energy production
Promoting muscle health
Longevity effects
Improved metabolic health
Promotes DNA repair
