This is what happens when you take NMN!
hour 1
NMN penetrates the cells
According to research, NMN is fast-acting . Preclinical studies on the pharmacokinetics of NMN suggest that it is absorbed from the gut into the bloodstream within minutes and transported to tissues within 10 to 30 minutes [1, 2]. Then the magic (or biochemistry) begins!
The NMN is immediately used for NAD+ biosynthesis .
Research suggests that rapid uptake is enabled by an NMN-specific transporter called “Sic12a8.”
hour 5
More activity in the cells
Same day, more activity in cells . Human studies show that NAD+ metabolites in blood plasma increase within the first few hours after NMN ingestion - and do so continuously, indicating increased utilization of NAD+ in cells and tissues [4].
Cells already use increased NAD+ levels to support hundreds of important cellular processes .
If you could communicate with your cells, they would definitely thank you! :)
Day 2
Happy Mitochondria
NAD+ levels continue to rise and now benefit the power plants of your cells and the place where cellular energy is generated: the mitochondria.
A preclinical study has shown that a three-day treatment of human kidney cells with NMN leads to increased mitochondrial replication [5]. An increased number of mitochondria enables more efficient energy production and metabolic regulation in the cell .
day 30
Up to 40% increase in NAD+
The fact is: After one month, the NAD+ level in the blood is up to 40% higher than when you took the first capsules.
They will stay at this level if you continue to supplement. This is according to a human clinical study that investigated NMN supplementation with a dose of 250 mg NMN per day in healthy adults [7].
Do you already feel the increased fitness?
week 6
Benefits for the muscles
We move from cells to systems because aspects of your fitness can improve. A human clinical study showed that NAD+ is one of the most depleted metabolites in aging muscle and that high NAD+ was associated with healthy muscle function [8].
Another clinical study found that oral NMN at a dose of 250 mg per day for 6 weeks improved muscle strength and performance in healthy older men [19].
week 8
Improved skin
How does your skin look? Advanced glycation end products (AGEs) are markers of skin aging. A clinical study in healthy postmenopausal women found that eight weeks of NMN supplementation with 300mg NMN per day resulted in a decrease in AGEs in the skin , which is considered a positive effect for skin aging [10].
week 10
Healthy insulin sensitivity
There is still more to happen in your muscles after 10 weeks.
In a clinical study of prediabetic women, two important discoveries were made. The first was an increase in NMN metabolites in skeletal muscle tissue , suggesting that the muscles had more NAD+ available.
The second finding suggests that NMN can support healthy insulin sensitivity in skeletal muscle and regulate the expression of genes related to muscle turnover - the turnover of muscle proteins, organelles and cell populations. The study participants took 250 mg of NMN daily [11].
month 3
Faster walking and longer telomeres
Three months have passed and you have measured 40% more NAD+ in your cells and tissues for 60 days. But what has changed physically in you? A lot, as clinical studies show!
One study found an improvement in gait speed (walking speed) in healthy elderly men taking 250mg of NMN per day [9]. Another study found that telomere length in peripheral blood mononuclear cells doubled at a dose of 300mg of NMN per day, indicating a younger biological age! [12].
month 6
It all starts to add up
A lot happens in six months - what has changed in your life?
With beLIVELY NMN, everything starts to add up to systemic health benefits . It sustainably supports multiple tissues and systems by attacking metabolic aging where it counts - in your cells.
Have you ever thought about having your biological age determined? After 6 months of taking NMN, it can be much lower than before, because your cells have finally found the energy driver they needed - NMN !
1 year
Healthy aging and NAD+ go hand in hand
Congratulations on your first year of replenishing the NAD+ lost through aging. Research shows that NAD+ declines by as much as 50% every 20 years .
It's important to stick with your NMN routine: research has shown that four weeks after stopping NMN, NAD+ levels returned to pre-supplementation levels [7]. Just like with exercise, sleep, and diet, consistency is key to long-term results.
Human studies are beginning to show that healthy aging and high NAD+ levels go hand in hand [8].
beLIVELY NMN helps you feel good as you get older!
NMN in powder form
to the productNMN in capsule form
To the product[1] Yoshino, J., et al., Cell Metab. 14: 528–536 (2011).
[2] Mills, K. F. et al. Cell Metab. 24: 795–806 (2016).
[3] Grozio, A., et al., Nature Metabolism 1: 47-57 (2019).
[4] Irie, J., et al., Endocrine Journal 67 (2): 153-160 (2020).
[5] Nomiyama, T., et al., The Journal of Biochemistry 171 (3): 325-338 (2021).
[6] Fu, J., et al.,J Biol Chem. 287 (29): 24460–24472 (2012).
[7] Okabe, K., et al., Frontiers in Nutrition 9: 868640 (2022).
[8] Igarashi, M. et al., NPG Aging 8: 5 (2022).
[9] Janssens, G.E. et al., Nat Aging 2: 254–263 (2022).
[10] Morita, Y. et al., Glycative Stress Research 9 (2): 33-41 (2022).
[11] Yoshino, M. et al., Science 372 (6547): 1224-1229 (2021).