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Drug influences on the blood vessels: A closer look at Ritalin and other substances
Introduction: The use of medications to treat various health conditions has increased significantly in recent years. One of the most well-known drugs is Ritalin, which is often used to treat attention deficit hyperactivity disorder (ADHD). Although such drugs can have positive effects on neurological functions, it is important to understand their potential effects on other body systems as well. In this blog post, we take a closer look at how drugs like Ritalin and others can affect blood vessels. 1. Ritalin and blood vessels: making a connection Ritalin , or generically methylphenidate, is a stimulant drug used primarily to treat ADHD. It works by increasing the levels of neurotransmitters such as dopamine in the brain. However, Ritalin also has effects on the peripheral nervous system, particularly the cardiovascular system. Studies suggest that Ritalin may increase the activity of the sympathetic nervous system, a part of the autonomic nervous system. Activation of the sympathetic nervous system leads to increased release of norepinephrine, a neurotransmitter known to constrict blood vessels. This may lead to an increase in blood pressure. 2. Mechanisms of blood vessel constriction Vasoconstriction, i.e. the narrowing of the blood vessels, can be based on several mechanisms. When Ritalin is taken, the sympathetic nervous system is activated, which leads to the release of noradrenaline. Noradrenaline binds to specific receptors on the smooth muscle cells of the blood vessels. This triggers a contraction of these muscles, which leads to a narrowing of the blood vessels. The increased peripheral resistance leads to an increase in blood pressure. 3. Other medications and their effects It is important to recognize that not only Ritalin, but also other medications can affect blood vessels. For example, beta-blockers, often used to treat high blood pressure, are designed to widen blood vessels to lower blood pressure. On the other hand, certain migraine medications, particularly triptans, can cause vasoconstriction. This highlights that different medications can have different effects on blood vessels depending on their specific mode of action. 4. Important considerations and precautions For people taking medications such as Ritalin, regular monitoring of blood pressure is crucial. This is especially important for people with pre-existing cardiovascular disease. The narrowing of blood vessels can increase the risk of cardiovascular complications. Therefore, it is advisable to discuss possible risks with the treating doctor before starting drug therapy. The doctor can recommend individual precautions and emphasize the need for regular check-ups to detect and manage unwanted effects early. Open communication between patient and doctor is key to ensuring safe and effective treatment. Conclusion: The effects of medications on blood vessels are varied and can vary depending on the active ingredient. When using medications such as Ritalin, it is crucial to understand the potential effects on blood pressure and take appropriate precautions. Open communication with the treating doctor and regular check-ups are essential to ensure the patient's health.
Learn moreNMN study reveals promising results for health and longevity
At beLIVELY, we are always on the lookout for the latest findings and innovations in the field of health and longevity . Today, we are pleased to share exciting news from a study that highlights the potential benefits of β-nicotinamide mononucleotide (NMN) for the human body. However, we would like to point out that NMN, According to German and European law, it is a chemical that is not suitable for human consumption. Furthermore, the sale of NMN as a food supplement is not permitted in Europe. NMN and its promising effects Animal studies have already shown that supplementing with NMN increases the concentration of nicotinamide adenine dinucleotide (NAD) in the body and significantly improves health span and lifespan . Even more promising, these effects occurred in animals without any safety concerns. The big question, however, was: Can these positive results be transferred to humans? The groundbreaking NMN study A randomized, double-blind, placebo-controlled study of 80 healthy middle-aged adults was conducted to answer this question. Over a period of 60 days, participants received a daily oral dose of placebo, 300 mg, 600 mg, or 900 mg of NMN. The results of this study are extremely revealing: All NMN-treated groups showed significant increases in blood NAD concentrations on days 30 and 60 compared to the placebo group and baseline (p ≤ 0.001). Most notably, the highest NAD concentrations were measured in the 600 mg and 900 mg NMN groups. No safety concerns were identified. No side effects or problems with laboratory or clinical measurements occurred, and the NMN supplement was well tolerated. Physical performance , measured by a six-minute walk test, was significantly higher in the NMN groups (300 mg, 600 mg, and 900 mg) than in the placebo group. The greatest improvements were observed in the 600 mg and 900 mg NMN groups. The biological age of the blood remained unchanged in the NMN groups, while it increased significantly in the placebo group. The study results indicate improved health , including better subjective health assessments. What does this mean for you? This study is a milestone toward a deeper understanding of the benefits of NMN for humans. It shows not only that NMN is safe and well tolerated , but also that it has the potential to improve health and physical performance. But it is to expressly point out that, according to German and European law, NMN is a chemical that is not suitable for human consumption. Furthermore, the sale of NMN as a food supplement is not permitted in Europe. In addition, the available number of studies is not sufficient to draw definitive conclusions: individual studies do not provide reliable evidence. Measuring your biological age At beLIVELY, we believe in the importance of data and facts to support your longevity journey, which is why we also offer you the opportunity to measure your biological age. With our biological age test, you can determine your current biological age and then measure it again after taking NMN and Resveratrol. The results will help you track your progress and achieve your health goals. We invite you to explore our products and begin your journey to a healthier and longer life. At beLIVELY, we believe that health and longevity are in your hands. Start today!
Learn moreWhat is Resveratrol?
What is Resveratrol? Resveratrol: An antioxidant from the polyphenol family Resveratrol is a phytochemical, specifically a polyphenol, and acts as an antioxidant molecule . These phytochemicals, which also function as plant hormones or substances that give color, scent, flavor, and defense, help plants protect and reproduce. Polyphenols, including resveratrol, have been shown in scientific studies to have antioxidant and anti-inflammatory properties. David Sinclair's research even discusses resveratrol as a molecule with potential longevity-promoting properties. He calls it a " longevity molecule." Trans-Resveratrol: The bioavailable variant Resveratrol exists in two isomeric forms - trans-resveratrol and cis-resveratrol. These isomers differ in a slight chemical modification of their molecular structure, which has significant effects on their stability and bioavailability. Trans-resveratrol is characterized by research results that show greater stability and better bioavailability . This means that it can be absorbed and used more effectively by our bodies. (Red wine and cheese - a French tradition) Red wine and fatty food - the secret from France The " French paradox " reveals how French people enjoy a long life expectancy despite a diet rich in fats and regular consumption of red wine. A major factor behind this phenomenon is resveratrol, a polyphenol abundant in certain red wine varieties such as Pinot Noir. With a resveratrol concentration of up to 2.78 mg per 100 milliliters, Pinot Noir has antioxidant and anti-inflammatory properties that can contribute to health. Interestingly, the fat commonly found in French cuisine plays an important role in the absorption of resveratrol . Since resveratrol is fat-soluble, consuming fats makes it easier for the body to absorb this polyphenol. This may explain why the combination of a high-fat diet and moderate red wine consumption has synergistic effects on health and longevity. Not only does resveratrol support heart health and counteract aging processes, but it is also more effectively absorbed by the body thanks to the high-fat French cuisine, providing a plausible explanation for the "French paradox." The Role of Antioxidants: Direct and Indirect Effects An antioxidant basically has an opposing effect - it is "anti", i.e. directed against something. The term "oxidant" refers to oxygen radicals, which antioxidants target. These molecules support the body by capturing free radicals, binding to them and thus neutralizing them. Resveratrol is known for exactly this ability. In addition, there are traditional antioxidants such as vitamins A, C, E, beta-carotene and selenium. Although the market for these vitamins as supplements is large, comprehensive studies have not shown any significant benefits of such supplementation. Indirect antioxidant effect In addition to the direct neutralization of oxygen radicals, an alternative mechanism of antioxidation exists that operates via the transcription factor Nrf2. Resveratrol can activate this factor, which modulates the transcription of DNA and thus influences inflammatory responses and oxidative stress. Nrf2 is crucial for the activation of genes that enhance cell protection in response to such stressful conditions and thus plays a key role in promoting cellular resilience. Resveratrol: A Focus of Science Resveratrol, a versatile molecule in the human body, acts on several levels. It strengthens the antioxidant system through direct and indirect mechanisms, thus promoting vital protective functions. It shows protective effects against cardiovascular diseases and neurological conditions such as Alzheimer's and also has potential anti-cancer properties. Clinical studies have found positive effects on systolic blood pressure in hypertensive patients and a reduction in blood sugar levels in diabetes mellitus. In vitro studies highlight resveratrol's role as an activator of sirtuins, known from research on nicotinamide adenine dinucleotide (NAD), and its ability to extend lifespan. The list of its health benefits is constantly growing. However, there is also evidence of negative effects from excessive supplementation, a phenomenon known as "hormesis" - the principle that the dose makes the poison. Critical effects only occur at very high doses. For example, a dose of 450 mg per day for a person weighing 60 kg was considered safe. For resveratrol-rich Pinot Noir, this would be equivalent to about 22 bottles of wine. Thanks to research, the molecule can now be isolated and consumed in its pure form, maximizing the benefits and minimizing potential risks. (Resveratrol in powder form) Natural Sources of Resveratrol Resveratrol, a widely studied molecule, is found in berries, nuts and dark chocolate. However, the highest levels of resveratrol are found in grape skins. During winemaking, grapes remain in wine barrels with their skins and seeds for an extended period of time. The fermentation process, in which the grape juice is in contact with the grape skins and seeds for a longer period of time, leads to an accumulation of resveratrol in the wine, making it richer in resveratrol than grape juice. In addition, the size of the grapes and the ratio of skin to pulp significantly influence the resveratrol content. Climatic and environmental conditions in the growing area also play a role: plants that grow in wetter areas and are more exposed to parasites and fungal infections tend to have higher levels of resveratrol. In other words, the more challenging the environmental conditions, the greater the proportion of resveratrol in the plants. Optimal absorption of resveratrol Since resveratrol is fat-soluble and does not dissolve in water, adding the powder to a glass of water to take it is not the most effective method. Instead, taking it with high-fat foods , such as yogurt or a tablespoon of oil, improves the bioavailability of resveratrol. The powder tastes a little sour, but is generally pleasant, and it is characterized by a yellowish color and a berry and grape-like scent, reflecting its natural origin. In addition, it is recommended to take resveratrol preferably early in the morning on an empty stomach to ensure optimal absorption before consuming other foods. Disclaimer: Scientific foundation The content of this blog is based on scientific studies. For a more in-depth insight into the topics covered, the associated research papers are linked. It is our aim to provide information based on sound scientific findings ( R , R , R , R , R , R , R , R , R )
Learn moreThe importance of flexibility and stretching for body and mind
A flexible body and a clear mind are two fundamental elements to living a healthy and fulfilling life. One important practice to achieve these goals is regular stretching. In this blog post, we explore the importance of flexibility and stretching for the body and mind, and the many benefits they offer. Improved quality of movement: Good mobility allows us to move our bodies naturally. Stretching makes our muscles and joints more flexible, which leads to improved posture and greater freedom of movement. Good quality of movement helps us stay active in everyday life and also supports us when doing sports or other physical activities. Stress relief and mental relaxation: Stretching not only has physical benefits, but also has a positive effect on our mind. While stretching, we can focus on our body and breathing, which leads to a reduction in stress and tension. It allows us to find a moment of calm and quiet the mind, which has a positive effect on our overall well-being. Relaxed muscles and relieve tension: Our modern lifestyles, often characterized by long hours of sitting and inactivity, can lead to muscle tension and shortening. Stretching allows us to release this tension and relax our muscles. Regular stretching helps improve muscle flexibility and supports the health of the musculoskeletal system. Improved circulation and accelerated recovery: Stretching increases blood flow to the muscles, which leads to better oxygen and nutrient delivery. This is especially important for making the muscles work more effectively and preventing injuries. In addition, improved circulation helps the muscles recover faster after training or physical exertion. Increased energy and concentration: Stretching can also increase our energy and improve concentration. By consciously focusing on our body and breathing, we can calm our mind and clear our thoughts. This helps us to have more presence and focus in everyday life and to better cope with daily challenges. Stretching should become a regular practice in our lives. There are many different types of stretching exercises that are suitable for different parts of the body and needs. It is important that we listen to our body and stretch it mindfully, without overexerting ourselves or causing pain.
Learn moreCoffee and Health: Everything You Should Know
Coffee is one of the most popular beverages in the world and is consumed by many people on a daily basis. Most of us reach for coffee to stay awake and productive or just to enjoy the taste. But what about the effect of coffee on health? Is coffee good for us or should we avoid it? In this blog post, we take a closer look at coffee and its effects on health. The Benefits of Coffee Coffee contains a variety of compounds and antioxidants that can have positive health effects. Here are some of the main benefits of coffee: Increases mental performance: Coffee contains caffeine, which stimulates the central nervous system and improves alertness and concentration. May reduce the risk of type 2 diabetes: Several studies have shown that regular coffee consumption may reduce the risk of type 2 diabetes. Protects against liver disease: Coffee can protect the liver and reduce the risk of liver diseases such as cirrhosis and liver cancer. May reduce the risk of cardiovascular disease: Some studies have shown that regular coffee consumption may reduce the risk of cardiovascular diseases such as heart attack and stroke. May reduce the risk of depression: Caffeine may help reduce the risk of depression. The Disadvantages of Coffee Although coffee has many benefits, there are also some disadvantages that should be considered. Here are some of the possible negative effects of coffee: May cause anxiety: Caffeine may cause anxiety and nervousness in some people. May affect sleep: Caffeine can interfere with sleep and lead to insomnia. May increase blood pressure: Caffeine can increase blood pressure and cause heart palpitations and irregular heartbeats in some people. May cause acid reflux and indigestion: Caffeine can irritate the stomach and cause acid reflux and indigestion in some people. Conclusion Overall, coffee in moderation is a safe and healthy beverage for most people. If you enjoy coffee and want to reap its benefits, then it's important to be aware of your personal tolerance levels and potential side effects. For example, if you have trouble sleeping, you should limit your coffee consumption or, better yet, avoid drinking it altogether. Some studies suggest that coffee may also reduce the risk of liver cancer. A 2017 meta-analysis that included data from 26 studies found that the risk of liver cancer is reduced by 20% in people who drink at least one cup of coffee daily. In addition, coffee can also improve cognitive abilities. A 2020 study showed that people who drink coffee regularly scored better on cognitive tests compared to non-coffee drinkers. However, it is important to note that coffee can also have negative effects on some people. Caffeine can cause anxiety, sleep problems, or stomach problems in some people. In addition, coffee can increase the risk of premature birth in pregnant women. Overall, however, coffee is a relatively safe and healthy beverage option as long as it is consumed in moderation. It is recommended that you consume no more than 400 mg of caffeine per day, which is roughly equivalent to 4 cups of coffee. So overall, there are many good reasons to drink coffee. While coffee is not the only way to stay healthy, it can definitely help promote good health. If you enjoy coffee, it's best to drink it in moderation and be aware of any potential negative effects on your health.
Learn moreHow artificial intelligence could stop aging...
Introduction Aging is a natural process that is unavoidable. However, it is also a process that brings with it many challenges, such as age-related diseases and limitations in physical and mental abilities. In recent years, artificial intelligence (AI) has made amazing progress, and there is increasing evidence that it could help slow down the aging process and prevent aging. Artificial Intelligence (AI) in the Medical and Healthcare Industry One of the areas where AI could be used to combat aging is medicine. AI-based diagnostic tools could help detect and treat age-related diseases such as cancer, diabetes and cardiovascular disease earlier. By using AI, doctors could also create personalized treatment plans based on a patient's individual needs and characteristics. (Human Health in the Hands of Artificial Intelligence) Another approach is to develop AI-based technologies that could slow or reverse aging. A promising example of this is using AI to identify drugs that could affect aging. By analyzing data from various sources, such as genetic information and medical studies, AI could help identify new drugs that could slow or even reverse aging. One of these substances could be something called nicotinamide mononucleotide (NMN) . AI could also play an important role in the area of health monitoring and prevention. Wearable technologies such as smartwatches and fitness trackers can already be used to collect and monitor health data. AI-based analyses of this data could help to detect early signs of health problems and take preventive measures. Finally, AI could also help address the social and economic impacts of ageing. Developing AI-based systems that help older people remain independent and maintain social connections for longer could reduce feelings of isolation and loneliness in old age. Additionally, AI could help mitigate the economic impact of demographic change by supporting older workers and helping companies adapt to an ageing workforce. Conclusion Overall, it is clear that AI has the potential to have a significant impact on the aging process. Of course, there are still many challenges to overcome before AI-based solutions can be used in practice. Nevertheless, it is exciting to see how AI could help in the future to overcome the challenges of aging and improve the quality of life of older people. NMN remains one of the most favored substances that can reverse aging.
Learn moreThe best cosmetic products for men
Cosmetics only for women? The beauty industry has changed a lot in recent years. In the past, cosmetic products were almost exclusively for women, but today there are more and more offerings for men. These products are specifically designed for men's needs and can help men look and feel better. One of the reasons men should use cosmetic products is because they can help reduce blemishes and acne. Many men have problems with oily skin and acne, and there are special products that can help solve these problems. For example, there are special cleansers and moisturizers that can help clean the pores and soothe the skin. Another reason why men should use cosmetic products is that they can help delay skin aging. When men take care of their skin regularly, they can help keep the skin looking young and healthy for longer. There are special anti-aging products that can help tighten the skin and reduce wrinkles. The best cosmetic products for men Cleanser: A good cleanser is the first step to maintaining clean and healthy skin. Products like the beLIVELY Charcoal Cleanser are popular with men. This cleanses the skin down to the deepest pore. Moisturizer: A moisturizer helps keep the skin supple and healthy. A popular product for men is the Moisturizing Balm from beLIVELY . This can also be used by women. Shaving cream: A good shaving cream ensures that the skin is protected from razors and makes shaving more comfortable. Popular products are the Proraso Pre-Shave Cream and the Nivea Men Sensitive Shaving Cream . After-shave: An after-shave balm helps to soothe and nourish the skin after shaving. Popular products include Burt's Bees Men's Aftershave and Kiehl's Facial Fuel No-Shine Moisturizing Lip Balm Sunscreen: Sunscreen is important to protect the skin from harmful UV rays. Popular products for men include Neutrogena Men's Sunscreen Lotion and Brickell Men's Daily Essential Face Sun Protection. Probably the most popular men’s skin care set is the Skin Pro Bundle, currently discounted by beLIVELY. The Skin Bundle Pro Set is the best that men's skincare has to offer for healthy, glowing skin. This easy-care 3-step anti-aging routine helps prevent breakouts, even skin tone, and fade acne scars. Expertly formulated to provide a balanced blend of moisturizing, cleansing, and exfoliating, this set is everything you need to bring out your best skin.
Learn moreFight wrinkles successfully - secret trick
Fact: Wrinkles can be fought Wrinkles are a natural part of the aging process, but that doesn't mean you can't fight them. With the right skincare routines and products, you can improve the look of wrinkles and slow their formation. One of the most important measures to combat wrinkles is the daily use of sunscreen. UV rays are one of the main causes of the formation of wrinkles and pigment spots. A sunscreen with a high SPF should be used every day to protect the skin from harmful UV rays. moisturizers Another important measure is the use of moisturizers. Wrinkles are often caused by dry skin and the use of moisturizers can help keep the skin supple and elastic. A cream with hyaluronic acid can be particularly effective as it binds moisture in the skin and thus makes the skin look smoother. Another effective anti-wrinkle treatment is anti-aging products that contain retinol. Retinol stimulates collagen production and can help make skin look firmer and smoother. However, products containing retinol should only be used under the supervision of a dermatologist or skin care professional, as they can make skin more sensitive to UV rays. Does nutrition play a role? Eating a balanced diet, getting enough sleep and drinking enough water can also help keep skin looking healthy and youthful. Avoid smoking and limit alcohol consumption, as these factors can accelerate skin aging. It is important to note that every person has different skin needs and it is important to choose the right products for your skin. NMN - A scientific sensation? Regardless of skin type, this supplement is a true miracle product: According to numerous studies, the molecule nicotinamide mononucleotide can measurably extend lifespan. NMN is the abbreviation for this exact molecule. With the NMN - beLIVELY pills you can experience this effect for yourself. What would a life be like in which you lose more and more wrinkles as you get older? Hard to imagine, isn't it? But with today's science it's actually possible!
Learn moreSlow aging: Three tips for a longer & healthier life
Slower Aging: 3 Tips for a Longer Life Who wouldn't want to live young and fit in a few years? We'll show you three tips that will help you take your aging into your own hands. Age more slowly to live healthily for longer in the future. Tip 1: Regular exercise Hobby athletes live longer. Regular, light exercise (not extreme sports) can help prevent numerous illnesses and obesity. On average, life expectancy can be extended by up to 10 years if you exercise twice a week. Tip 2: Sustainable nutrition Those who eat mainly fruit and vegetables and as unprocessed foods as possible can expect to live longer. Fast food and pre-cooked food, on the other hand, are negative. Tip 3: Protect your DNA with NMN But no matter how much you exercise and how healthy you eat, one day your body will still age. The reason is a lack of NMN, also known as nicotinamide mononucleotide, which is essential for DNA repair. Fortunately, this molecule can now be produced synthetically in complex processes and supplied externally. Conclusion: Start now! First and foremost, it comes down to three factors: regular exercise, a sustainable diet and protecting your DNA by taking nicotinamide mononucleotide, or NMN for short. With these three tips, you will live longer, healthier and age more slowly. On beLIVELY, you can put the third tip into practice straight away. With our NMN - beLIVELY pills, you can experience the effect of nicotinamide mononucleotide for yourself. Start now and live longer.
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